Maintain Serum Bicarbonate (HCO₃⁻) Levels of 22–26 mmol/LKeeping serum bicarbonate levels within 22–26 mmol/L may help slow CKD progression and support muscle preservation. Monitor Blood Pressure, Edema, and ElectrolytesIf you have hypertension, heart failure, or… Sodium Bicarbonate Supplementation for Chronic Kidney Disease: Can It Help Preserve Muscle?